The abnormal cells that cause WM can produce a protein called B-cell lymphoma-2 (BCL-2) which helps the cells live for longer. BCL-2 inhibitors stop this protein from working so that the cells die.
There aren’t any BCL-2 inhibitors available to people with WM at the moment. However, a drug called venetoclax is being trialled in people with B-cell lymphomas, including WM.