The UK charity for Waldenstrom’s macroglobulinaemia – a rare type of blood cancer
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Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies (ELM-1)

Understanding the best doses for Odronextamb in patients with a type of protein on their B-cells
Main Aims

Some people with non-Hodgkin Lymphoma have a protein called CD20 on their B-cells. This study is focussed on a type of treatment that targets this protein, giving researchers insight into what the right dosage is, and looking at different ways of giving the drug.

This study is on-going but currently closed to recruitment.

Recruitment Criteria

• Confirmed WM diagnosis; and are documented as having the the CD20 protein

• Previously been treated with a minimum of 2 lines of systemic therapy including at least one line with an anti-CD20 treatment

• No further standard treatment options remaining

Recruitment status: Not Recruiting
Sponsor: Regeneron Pharmaceuticals
Expected to end: 30/09/2025
Phases: