The UK charity for Waldenstrom’s macroglobulinaemia – a rare type of blood cancer
Support Line: 0300 373 8500

Showing only trials that are South West England

A Long-term Extension Study of PCI-32765 (Ibrutinib) (CAN3001)
Studying the long-term effects of Ibrutinib in people who were on previous trials for the drug that have now closed
Expected to end: 29/01/2027
Study to Evaluate the Efficacy and Safety of Sonrotoclax in Participants With Waldenström’s Macroglobulinemia
Understanding the safety and efficacy of a new drug that stops a certain type of protein working
Expected to end: 01/09/2028
A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies
Testing a new treatment to understand it’s efficacy and the best dose for patients
Expected to end: 31/03/2028
Rituximab and Ibrutinib (RI) versus Dexamethasone, Rituximab and Cyclophosphamide (DRC) as Initial Therapy for Waldenström’s Macroglobulinaemia (RAINBOW)
Is ibrutinib and rituximab a more effective first-line treatment than the current standard first-line treatment for people with WM?
Expected to end: 01/03/2030
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
Measuring the safety and efficacy of nemtabrutinib, a type of BTK inhibitor
Expected to end: 19/03/2027
A Study of NX-5948 in Adults With Relapsed/​Refractory B-cell Malignancies
The first trial in humans for a new type of BTK degrader
Expected to end: 01/01/2028
A Study of Oral LOXO-305 in Patients With Previously Treated CLL/​SLL or NHL
Understanding the best dosage for a BTK inhibitor called Pirtobrutinib
Expected to end: 01/01/2028
An Open-label, Phase 2 Study of ACP-196 in Subjects With Waldenström Macroglobulinemia
Measuring the safety and efficacy of Acalabrutinib in people with WM
Expected to end: 31/12/2026
Oxford Pre-cancerous Lymphoproliferative Disorders Study (OxPLoreD)
Looking for markers that might predict disease is progressing
Expected to end: 01/10/2025
An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial
Studying long-term data for Venetoclax in people who were previously taking the drug on other trials
Expected to end: 01/02/2026