The UK charity for Waldenstrom’s macroglobulinaemia – a rare type of blood cancer
Support Line: 0300 373 8500

Showing only trials that are London

Study to Evaluate the Efficacy and Safety of Sonrotoclax in Participants With Waldenström’s Macroglobulinemia
Understanding the safety and efficacy of a new drug that stops a certain type of protein working
Expected to end: 01/09/2028
Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom Macroglobulinemia (CLOVER-WaM)
Measuring the efficacy of a drug called Iopofosine I131 in patients with WM
Expected to end: 22/12/2026
Rituximab and Ibrutinib (RI) versus Dexamethasone, Rituximab and Cyclophosphamide (DRC) as Initial Therapy for Waldenström’s Macroglobulinaemia (RAINBOW)
Is ibrutinib and rituximab a more effective first-line treatment than the current standard first-line treatment for people with WM?
Expected to end: 01/03/2030
A Long-term Extension Study of PCI-32765 (Ibrutinib) (CAN3001)
Studying the long-term effects of Ibrutinib in people who were on previous trials for the drug that have now closed
Expected to end: 29/01/2027
Study to Evualate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants with B-Cell Malignancies
Assessing the safety and effectiveness of a medication called ABBV-101 in people with certain types of relapsed non-Hodgkin’s lymphomas
Expected to end: 01/03/2031
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
Measuring the safety and efficacy of nemtabrutinib, a type of BTK inhibitor
Expected to end: 19/03/2027
A Study of NX-5948 in Adults With Relapsed/​Refractory B-cell Malignancies
The first trial in humans for a new type of BTK degrader
Expected to end: 01/01/2028
Study to Evaluate CCS1477 in Haematological Malignancies
Finding out more about a new type of targeted treatment
Expected to end: 30/06/2025
An Open-label, Phase 2 Study of ACP-196 in Subjects With Waldenström Macroglobulinemia
Measuring the safety and efficacy of Acalabrutinib in people with WM
Expected to end: 31/12/2026
Oxford Pre-cancerous Lymphoproliferative Disorders Study (OxPLoreD)
Looking for markers that might predict disease is progressing
Expected to end: 01/10/2025