The UK charity for Waldenstrom’s macroglobulinaemia – a rare type of blood cancer
Support Line: 0300 373 8500

What are BCL-2 inhibitors

BCL-2 inhibitors

The abnormal cells that cause WM can produce a protein called B-cell lymphoma-2 (BCL-2) which helps the cells live for longer. BCL-2 inhibitors stop this protein from working so that the cells die.

There aren’t any BCL-2 inhibitors available to people with WM at the moment. However, a drug called venetoclax is being trialled in people with B-cell lymphomas, including WM.

With a diagnosis of Waldenstrom’s macroglobulinaemia, you may be coming across new and unfamiliar words. Look them up in our WM glossary below.